How Obagi Systems Address Photoaging: Nu-Derm, Obagi-C Rx and the Obagi Blue Peel

Aging and sun exposure slow cell turnover and worsen lines, spots and texture. Obagi provides three clinical approaches: Nu-Derm for moderate to severe photodamage, Obagi-C Rx for vitamin C-based brightening and maintenance, and the Obagi Blue Peel (a TCA peel) for in-office exfoliation. All are typically supplied through licensed providers; a clinician should assess which is appropriate and manage sun protection and side effects.

Why aging skin changes

Sun exposure, stress and pollution slow skin cell turnover as you age. Old cells build up on the surface, which makes lines, uneven tone, age spots and loss of elasticity more visible. Dermatologic treatment aims to speed renewal, improve pigmentation and support collagen so skin looks healthier.

Three Obagi approaches used for photoaging

Obagi, a medical skincare brand, offers three well-known strategies that target these changes: the Nu-Derm System, the Obagi-C Rx System and the Obagi Blue Peel (a TCA peel performed in clinic). Each follows a different approach and intensity, and all are usually supplied through licensed providers.

Obagi Nu-Derm System

Nu-Derm is a multi-step regimen developed to treat moderate to severe sun damage and dyschromia. The program combines exfoliation agents and prescription-strength actives that work on the stratum corneum, epidermis and dermis to encourage cell turnover, correct pigmentation and support collagen remodeling. Providers typically tailor the protocol and monitor for irritation, because active ingredients can increase sun sensitivity.

Obagi-C Rx System

The Obagi-C Rx System emphasizes topical vitamin C to brighten skin and counteract oxidative damage. It is generally aimed at people with mild to moderate photodamage who want to even skin tone and support collagen production. The system is designed to be less aggressive than Nu-Derm, and many clinicians use it as a step-down maintenance program after stronger treatments.

Obagi Blue Peel (TCA peel)

The Obagi Blue Peel is an in-office chemical peel that uses trichloroacetic acid (TCA) blended with a colored base to help clinicians see application. It produces controlled exfoliation to improve texture, pigmentation and fine lines. Because it is a clinical procedure, a trained provider performs it, and downtime and aftercare vary with peel strength.

What to expect and choosing a path

All three approaches can improve signs of photoaging, but they differ in intensity, expected downtime and suitability. Nu-Derm targets more significant pigmentation and structural change. Obagi-C Rx focuses on antioxidant-based brightening and maintenance. The Blue Peel is a procedure for mechanical chemical exfoliation.

Discuss medical history, sun exposure, current skincare and medications with a dermatologist or licensed provider before starting any of these programs. They can confirm whether a prescription is required, recommend sun protection, and outline realistic timelines and side effects.

Safety note

Active medical-grade products and chemical peels can cause irritation, increased sun sensitivity and other side effects if used incorrectly. Work with a licensed clinician for assessment, dosing and follow-up.

1. Confirm current product names and whether Obagi Nu-Derm and Obagi-C Rx names or formulations have changed.
2. Verify which Obagi products require a prescription in the US and current distribution channels.
3. Check current pricing or kit availability for Nu-Derm, Obagi-C Rx and Obagi Blue Peel kits and update if needed.
4. Confirm manufacturer guidance and standardized protocols for the Obagi Blue Peel (TCA concentrations and recommended aftercare).